The Journal of Thoracic and Cardiovascular Surgery
Volume 133, Issue 6 , Pages 1573-1580.e2 , June 2007

Results of a multicenter clinical trial with the Thoratec Implantable Ventricular Assist Device⁎

  • Mark S. Slaughter, MD

      Affiliations

    • Advocate Christ Medical Center, Oak Lawn, Ill
    • Corresponding Author InformationAddress for reprints: Mark Slaughter, MD, Advocate Christ Medical Center, 4440 W 95th St, Suite 205, Oak Lawn, Il 60453.
    • ,
  • Steven S. Tsui, MD

      Affiliations

    • Papworth Hospital, Cambridge, UK
    • S.S.T. reports consulting and lecture fees and grant support from Ventracor (UK) Pty Ltd.
    • ,
  • Aly El-Banayosy, MD

      Affiliations

    • Heart Center NRW, Bad Oeynhausen, Germany
    • A.E-B. reports consulting fees from World-Heart.
    • ,
  • Benjamin C. Sun, MD

      Affiliations

    • Ohio State University, Columbus, Ohio
    • B.S. reports consulting and lecture fees from Thoratec Corporation and lecture fees from and equity ownership in ABIOMED, Inc.
    • ,
  • Robert L. Kormos, MD

      Affiliations

    • University of Pittsburgh Medical Center, Pittsburgh, Pa
    • R.L.K. reports fellowship support from Thoratec Corporation.
    • ,
  • Dale K. Mueller, MD

      Affiliations

    • OSF St Francis Medical Center, Peoria, Ill
    • ,
  • H. Todd Massey, MD

      Affiliations

    • University of Rochester, Rochester, NY
    • ,
  • Timothy B. Icenogle, MD

      Affiliations

    • Sacred Heart Medical Center, Spokane, Wash
    • T.B.I. reports lecture fees from Thoratec Corporation.
    • ,
  • David J. Farrar, PhD

      Affiliations

    • Thoratec Corporation, Pleasanton, Calif
    • D.J.F. reports employment by and equity ownership in Thoratec Corporation.
    • ,
  • J. Donald Hill, MD

      Affiliations

    • University of California Medical Center, San Francisco, Calif.
    • J.D.H. reports consulting fees from and equity ownership in Thoratec Corporation.
    • ,
  • IVAD Study Group

Received 31 August 2006 ,Revised 6 December 2006 ,Accepted 12 December 2006.

References 

  1. DeBakey ME. Left ventricular bypass pump for cardiac assistance: clinical experience. Am J Cardiol. 1971;27:3–11
  2. Litwak RS, Koffsky RM, Jurado RA, Lukban SB, Ortiz AF, Fischer AP, et al. Use of a left heart assist device after intracardiac surgery: technique and clinical experience. Ann Thorac Surg. 1976;21:191–202
  3. Norman JC, Duncan JM, Frazier OH, Hallman GL, Ott DA, Reul GJ, et al. Intracorporeal (abdominal) left ventricular assist devices or partial artificial hearts: A five-year clinical experience. Arch Surg. 1981;116:1441–1445
  4. Pennington DG, Merjavy JP, Swartz MT, Codd JE, Barner HB, Lagunoff D, et al. The importance of biventricular failure in patients with postoperative cardiogenic shock. Ann Thorac Surg. 1985;3:170–178
  5. Korfer R, el-Banayosy A, Posival H, Minami K, Korner MM, Arusoglu L, et al. Mechanical circulatory support: the Bad Oeynhausen experience. Ann Thorac Surg. 1995;59(2 Suppl):S56–S63
  6. Frazier OH, Rose EA, McCarthy P, Burton NA, Tector A, Levin H, et al. Improved mortality and rehabilitation of transplant candidates treated with a long-term implantable left ventricular assist system. Ann Surg. 1995;222:327–338
  7. Farrar DJ, Hill JD, Pennington DG, McBride LR, Holman WL, Kormos RL, et al. Preoperative and postoperative comparison of patients with univentricular and biventricular support with the Thoratec ventricular assist device as a bridge to cardiac transplantation. J Thorac Cardiovasc Surg. 1997;113:202–209
  8. McBride LR, Naunheim KS, Fiore AC, Moroney DA, Swartz MT. Clinical experience with 111 Thoratec ventricular assist devices. Ann Thorac Surg. 1999;67:1233–1239
  9. McCarthy PM, Smedira NO, Vargo RL, Goormastic M, Hobbs RE, Starling RC, et al. One hundred patients with the HeartMate left ventricular assist device: evolving concepts and technology. J Thorac Cardiovasc Surg. 1998;115:904–912
  10. Frazier OH, Rose EA, Oz MC, Dembitsky W, McCarthy P, Radovancevic B, et al. Multicenter clinical evaluation of the HeartMate vented electric left ventricular assist system in patients awaiting heart transplantation. J Thorac Cardiovasc Surg. 2001;122:1186–1195
  11. World Heart Inc. Physician’s manual. Oakland (CA): World Heart Inc; 2004;Novacor LVAS, Catalog No. N20099
  12. Morgan JA, John R, Rao V, Weinberg AD, Lee BJ, Mazzeo PA, et al. Bridging to transplant with the HeartMate left ventricular assist device: the Columbia Presbyterian 12-year experience. J Thorac Cardiovasc Surg. 2004;127:1309–1316
  13. Copeland JG, Smith RG, Arabia FA, Nolan PE, Sethi GK, Tsau PH, et al. Cardiac replacement with a total artificial heart as a bridge to transplantation. N Engl J Med. 2004;351:859–867
  14. Rose EA, Gelijns AC, Moskowitz AJ, Heitjan DF, Stevenson LW, Dembitsky W, et al. Long-term mechanical left ventricular assistance for end-stage heart failure. N Engl J Med. 2001;345:1435–1443
  15. Park SJ, Tector A, Piccioni W, Raines E, Gelijns A, Moskowitz A, et al. Left ventricular assist devices as destination therapy: a new look at survival. J Thorac Cardiovasc Surg. 2005;129:9–17
  16. Long JW, Kfoury AG, Slaughter MS, Silver M, Milano C, Rogers J, et al. Long-term destination therapy with the HeartMate XVE left ventricular assist device: improved outcomes since the REMATCH study. Congest Heart Fail. 2005;11:133–138
  17. Pierce WS, Donachy JH, Landis DL, Brighton JA, Rosenberg G, Migliore JJ, et al. Prolonged mechanical support of the left ventricle. Circulation. 1978;58(3 Pt 2):I133–I146
  18. Farrar DJ, Reichenbach SH, Rossi SA, Weidman JR. Development of an intracorporeal Thoratec ventricular assist device for univentricular or biventricular support. ASAIO J. 2000;46:351–353
  19. Reichenbach SH, Farrar DJ, Hill JD. A versatile intracorporeal ventricular assist device based on the Thoratec VAD system. Ann Thorac Surg. 2001;71(Suppl 3):S171–S175
  20. Thoratec Corporation. Thoratec ventricular assist device instructions for use, document 15003H. Pleasanton (CA): Thoratec Corporation; 2004;
  21. Kormos RL, Gasior TA, Kawai A, Pham SM, Murali S, Hattler BG, et al. Transplant candidate’s clinical status rather than right ventricular function defines need for univentricular versus biventricular support. J Thorac Cardiovasc Surg. 1996;111:773–783
  22. Magliato KE, Kleisli T, Soukiasian HJ, Tabrizi R, Coleman B, Hickey A, et al. Biventricular support in patients with profound cardiogenic shock: a single center experience. ASAIO J. 2003;49:475–479
  23. El-Banayosy A, Arusoglu L, Kizner L, Tenderich G, Boethig D, Minami K, et al. Predictors of survival in patients bridged to transplantation with the Thoratec VAD device: a single-center retrospective study on more than 100 patients. J Heart Lung Transplant. 2000;19:964–968
  24. Tsukui H, Teuteberg JJ, Murali S, McNamara DM, Buchanan JR, Winowich S, et al. Biventricular assist device utilization for patients with morbid congestive heart failure: a justifiable strategy. Circulation. 2005;112:I65–I72Suppl
  25. Slaughter MS, Silver MA, Pappas PS, Tatooles AJ. Home discharge experience with the Thoratec LVAD TLC-II portable driver. [abstract] ASAIO J. 2002;48:130
  26. Reinhartz O, Hill JD, Al-Khaldi A, Pelletier MP, Robbins RC, Farrar DJ. Thoratec ventricular assist devices in pediatric patients: update on clinical results. ASAIO J. 2005;51:501–503

PII: S0022-5223(07)00058-X

doi: 10.1016/j.jtcvs.2006.11.050

The Journal of Thoracic and Cardiovascular Surgery
Volume 133, Issue 6 , Pages 1573-1580.e2 , June 2007

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