The Journal of Thoracic and Cardiovascular Surgery
Volume 133, Issue 3 , Pages 632-639 , March 2007

Over two decades of pediatric heart transplantation: How has survival changed?

Read at the Eighty-sixth Annual Meeting of The American Association for Thoracic Surgery, Philadelphia, Pa, April 29-May 3, 2006.

  • David L.S. Morales, MD

      Affiliations

    • Michael E. DeBakey Department of Surgery, Division of Congenital Heart Surgery, Baylor College of Medicine, Houston, Tex
    • Division of Congenital Heart Surgery, Texas Children’s Hospital, Houston, Tex
    • Corresponding Author InformationAddress for reprints: David L.S. Morales, MD, Division of Congenital Heart Surgery, Texas Children’s Hospital, 6621 Fannin St, MC-WT 19345H, Houston, TX 77030.
  • ,
  • William J. Dreyer, MD

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex
  • ,
  • Susan W. Denfield, MD

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex
  • ,
  • Jeffrey S. Heinle, MD

      Affiliations

    • Michael E. DeBakey Department of Surgery, Division of Congenital Heart Surgery, Baylor College of Medicine, Houston, Tex
    • Division of Congenital Heart Surgery, Texas Children’s Hospital, Houston, Tex
  • ,
  • E. Dean McKenzie, MD

      Affiliations

    • Michael E. DeBakey Department of Surgery, Division of Congenital Heart Surgery, Baylor College of Medicine, Houston, Tex
    • Division of Congenital Heart Surgery, Texas Children’s Hospital, Houston, Tex
  • ,
  • Daniel E. Graves, PhD

      Affiliations

    • Division of Congenital Heart Surgery, Texas Children’s Hospital, Houston, Tex
  • ,
  • Jack F. Price, MD

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex
  • ,
  • Jeffrey A. Towbin, MD

      Affiliations

    • Division of Pediatric Cardiology, Department of Pediatrics, Baylor College of Medicine, Houston, Tex
  • ,
  • O.H. Frazier, MD

      Affiliations

    • Texas Heart Institute at St Luke’s Episcopal Hospital, Department of Thoracic and Cardiovascular Surgery, Houston, Tex.
  • ,
  • Denton A. Cooley, MD

      Affiliations

    • Texas Heart Institute at St Luke’s Episcopal Hospital, Department of Thoracic and Cardiovascular Surgery, Houston, Tex.
  • ,
  • Charles D. Fraser Jr, MD

      Affiliations

    • Michael E. DeBakey Department of Surgery, Division of Congenital Heart Surgery, Baylor College of Medicine, Houston, Tex
    • Division of Congenital Heart Surgery, Texas Children’s Hospital, Houston, Tex

Received 29 April 2006 ,Revised 25 August 2006 ,Accepted 25 September 2006.

References 

  1. Kantrowitz A, Haller JD, Joos H, Cerruti MM, Carstensen HE. Transplantation of the heart in an infant and an adult. Am J Cardiol. 1968;22:782–790
  2. Barnard CN. The operation (A human cardiac transplant: an interim report of a successful operation performed at Groote Schuur Hospital, Cape Town). S Afr Med J. 1967;41:1271–1274
  3. Mendeloff EN. The history of pediatric heart and lung transplantation. Pediatr Transplant. 2002;6:270–279
  4. Cooley DA, Frazier OH, Van Buren CT, Bricker JT, Radovancevic B. Cardiac transplantation in an 8-month-old female infant with subendocardial fibroelastosis. JAMA. 1986;256:1326–1329
  5. Boucek MM, Edwards LB, Keck BM, Trulock EP, Taylor DO, Hertz MI. Registry of the International Society for Heart and Lung Transplantation: eighth official pediatric report—2005. J Heart Lung Transplant. 2005;24:968–982
  6. Bauer J, Thul J, Valeske K, Muller M, Michel-Behnke I, Gehron J, et al. Perioperative management in pediatric heart transplantation. Thorac Cardiovasc Surg. 2005;53(Suppl 2):S155–S158
  7. Ross M, Kouretas P, Gamberg P, Miller J, Burge M, Reitz B, et al. Ten- and 20-year survivors of pediatric orthotopic heart transplantation. J Heart Lung Transplant. 2006;25:261–270
  8. Lamour JM, Addonizio LJ. Pediatric heart transplantation. In:  Edwards NM,  Chen JM,  Mazzeo PA editor. Cardiac transplantation. Totowa [NJ]: Humana Press; 2004;p. 203–225
  9. Chen JM, Davies RR, Mital SR, Mercando ML, Addonizio LJ, Pinney SP, et al. Trends and outcomes in transplantation for complex congenital heart disease: 1984 to 2004. Ann Thorac Surg. 2004;78:1352–1361
  10. Groetzner J, Reichart B, Roemer U, Reichel S, Kozlik-Feldmann R, Tiete A, et al. Cardiac transplantation in pediatric patients: fifteen-year experience of a single center. Ann Thorac Surg. 2005;79:53–60
  11. Al Khaldi A, Oyer PE, Robbins RC. Outcome analysis of donor gender in heart transplantation. J Heart Lung Transplant. 2006;25:461–468
  12. Erinc K, Yamani MH, Starling RC, Young JB, Crowe T, Ratliff NB, et al. The influence of donor gender on allograft vasculopathy: evidence from intravascular ultrasound. Transplant Proc. 2004;36:3129–3131
  13. Mahle WT, Kanter KR, Vincent RN. Disparities in outcome for black patients after pediatric heart transplantation. J Pediatr. 2005;147:739–743
  14. Chin C, Naftel DC, Singh TP, Blume ED, Luikart H, Bernstein D, et al. Risk factors for recurrent rejection in pediatric heart transplantation: a multicenter experience. J Heart Lung Transplant. 2004;23:178–185
  15. Ringewald JM, Gidding SS, Crawford SE, Backer CL, Mavroudis C, Pahl E. Nonadherence is associated with late rejection in pediatric heart transplant recipients. J Pediatr. 2001;139:75–78

PII: S0022-5223(06)01950-7

doi: 10.1016/j.jtcvs.2006.09.055

The Journal of Thoracic and Cardiovascular Surgery
Volume 133, Issue 3 , Pages 632-639 , March 2007