The Journal of Thoracic and Cardiovascular Surgery
Volume 133, Issue 1 , Pages 2-6 , January 2007

Endocrine function is not impaired in patients with a continuous MicroMed–DeBakey axial flow pump

  • Georg M. Wieselthaler, MD

      Affiliations

    • Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
    • Ludwig Boltzmann Institute for Cardiosurgical Research, University of Vienna, Vienna, Austria.
  • ,
  • Michaela Riedl, MD

      Affiliations

    • Department of Medicine III, Clinical Division of Endocrinology and Metabolism, University of Vienna, Vienna, Austria
  • ,
  • Heinrich Schima, PhD

      Affiliations

    • Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
    • Ludwig Boltzmann Institute for Cardiosurgical Research, University of Vienna, Vienna, Austria.
  • ,
  • Oswald Wagner, MD

      Affiliations

    • Department of Laboratory Diagnostics, University of Vienna, Vienna, Austria
  • ,
  • Werner Waldhäusl, MD

      Affiliations

    • Department of Medicine III, Clinical Division of Endocrinology and Metabolism, University of Vienna, Vienna, Austria
  • ,
  • Ernst Wolner, MD

      Affiliations

    • Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
    • Ludwig Boltzmann Institute for Cardiosurgical Research, University of Vienna, Vienna, Austria.
  • ,
  • Anton Luger, MD

      Affiliations

    • Department of Medicine III, Clinical Division of Endocrinology and Metabolism, University of Vienna, Vienna, Austria
  • ,
  • Martin Clodi, MD

      Affiliations

    • Department of Medicine III, Clinical Division of Endocrinology and Metabolism, University of Vienna, Vienna, Austria
    • Corresponding Author InformationAddress for reprints: Martin Clodi, MD, Department of Medicine III, Clinical Division of Endocrinology and Metabolism, University of Vienna, Waehringer Guertel 18-20, A-1090 Vienna, Austria.

Received 12 July 2002 ,Revised 13 January 2003 ,Accepted 13 March 2003.

References 

  1. McCarthy PM, Smedira NO, Vargo RL, Goormastic M, Hobbs RE, Starling RC, et al. One hundred patients with the HeartMate left ventricular assist device: evolving concepts and technology. J Thorac Cardiovasc Surg. 1998;115:904–912
  2. el Banayosy A, Arusoglu L, Kizner L, Tenderich G, Minami K, Inoue K, et al. Novacor left ventricular assist system versus Heartmate vented electric left ventricular assist system as a long-term mechanical circulatory support device in bridging patients: a prospective study. J Thorac Cardiovasc Surg. 2000;119:581–587
  3. Wieselthaler GM, Schima H, Dworschak M, Quittan M, Nuhr M, Czerny M, et al. First experiences with outpatient care of patients with implanted axial flow pumps. Artif Organs. 2001;25:331–335
  4. Wieselthaler GM, Schima H, Hiesmayr M, Pacher R, Laufer G, Noon GP, et al. First clinical experience with the DeBakey VAD continuous-axial-flow pump for bridge to transplantation. Circulation. 2000;101:356–359
  5. Taylor KM, Wright GS, Reid JM, Bain WH, Caves PK, Walker MS, et al. Comparative studies of pulsatile and nonpulsatile flow during cardiopulmonary bypass (II. The effects on adrenal secretion of cortisol). J Thorac Cardiovasc Surg. 1978;75:574–578
  6. Yada I, Golding LR, Harasaki H, Jacobs G, Koike S, Yozu R, et al. Physiopathological studies of nonpulsatile blood flow in chronic models. Trans Am Soc Artif Intern Organs. 1983;29:520–525
  7. Altman DG. In: Practical statistics for medical research. London: Chapman and Hall; 1991;p. 431
  8. Murkin JM, Farrar JK, Tweed WA, McKenzie FN, Guiraudon G. Cerebral autoregulation and flow/metabolism coupling during cardiopulmonary bypass: the influence of PaCO2. Anesth Analg. 1987;66:825–832
  9. Anker SD, Chua TP, Ponikowski P, Harrington D, Swan JW, Kox WJ, et al. Hormonal changes and catabolic/anabolic imbalance in chronic heart failure and their importance for cardiac cachexia. Circulation. 1997;96:526–534
  10. Ascheim DD, Hryniewicz K. Thyroid hormone metabolism in patients with congestive heart failure: the low triiodothyronine state. Thyroid. 2002;12:511–515
  11. Limas CJ, Kroupis C, Haidaroglou A, Coccinons DV. Hyperprolactinemia in patients with heart failure: clinical and immunogenetic correlations. Eur J Clin Invest. 2002;32:74–78
  12. Consensus guidelines for the diagnosis and treatment of adults with growth hormone deficiency: summary statement of the Growth Hormone Research Society Workshop on Adult Growth Hormone Deficiency. J Clin Endocrinol Metab. 1998;83:379–381
  13. Fazio S, Sabatini D, Capaldo B, Vigorito C, Giordano A, Guida R, et al. A preliminary study of growth hormone in the treatment of dilated cardiomyopathy. N Engl J Med. 1996;334:809–814
  14. Colao A, Marzullo P, Di Somma C, Lombardi G. Growth hormone and the heart. Clin Endocrinol (Oxf). 2001;54:137–154
  15. Cuneo RC, Salomon F, Wiles CM, Hesp R, Sonksen PH. Growth hormone treatment in growth hormone-deficient adults (II. Effects on exercise performance). J Appl Physiol. 1991;70:695–700
  16. Ogawa K, Hirai M, Katsube T, Murayama M, Hamaguchi K, Shimakawa T, et al. Suppression of cellular immunity by surgical stress. Surgery. 2000;127:329–336
  17. Udelsman R, Holbrook NJ. Endocrine and molecular responses to surgical stress. Curr Probl Surg. 1994;31:653–720
  18. Rolih CA, Ober KP. The endocrine response to critical illness. Med Clin North Am. 1995;79:211–224
  19. Kono K, Philbin DM, Coggins CH, Slater EE, Triantafillou A, Levine FH, et al. Adrenocortical hormone levels during cardiopulmonary bypass with and without pulsatile flow. J Thorac Cardiovasc Surg. 1983;85:129–133
  20. Pollock EM, Pollock JC, Jamieson MP, Beastall GS, Wright C, Torsney B, et al. Adrenocortical hormone concentrations in children during cardiopulmonary bypass with and without pulsatile flow. Br J Anaesth. 1988;60:536–541
  21. Tsutsui T, Nose Y. Arterial pressure pulsation during nonpulsatile biventricular bypass experiments: possible idioperipheral pulsation. Artif Organs. 1986;10:153–155
  22. Delgado R, Radovancevic B, Massin EK, Frazier OH, Benedict C. Neurohormonal changes after implantation of a left ventricular assist system. ASAIO J. 1998;44:299–302
  23. Noirhomme P, Jacquet L, Underwood M, El Khoury G, Goenen M, Dion R. The effect of chronic mechanical circulatory support on neuroendocrine activation in patients with end-stage heart failure. Eur J Cardiothorac Surg. 1999;16:63–67
  24. Buket S, Alayunt A, Ozbaran M, Hamulu A, Discigil B, Cetindag B, et al. Effect of pulsatile flow during cardiopulmonary bypass on thyroid hormone metabolism. Ann Thorac Surg. 1994;58:93–96
  25. Gomberg-Maitland M, Frishman WH. Thyroid hormone and cardiovascular disease. Am Heart J. 1998;135:187–196

PII: S0022-5223(06)00862-2

doi: 10.1016/j.jtcvs.2003.03.006

The Journal of Thoracic and Cardiovascular Surgery
Volume 133, Issue 1 , Pages 2-6 , January 2007