« Previous Next » The Journal of Thoracic and Cardiovascular Surgery
Volume 131, Issue 3 , Pages 579-586.e3 , March 2006

The effect of anteroapical aneurysm plication on end-systolic three-dimensional strain in the sheep: A magnetic resonance imaging tagging study

Julius M. Guccione, PhD
- Department of Surgery, University of California, San Francisco
- Department of Veterans Affairs Medical Center, San Francisco, Calif
- Address for reprints: Julius M. Guccione, MD, Division of Surgical Services (112D), Department of Veterans Affairs Medical Center, 4150 Clement St, San Francisco, CA 94121
Joseph C. Walker, PhD
- Department of Bioengineering, University of California, San Francisco
Jeremy R. Beitler, BS
- Department of Veterans Affairs Medical Center, San Francisco, Calif
Scott M. Moonly, PhD
- Department of Bioengineering, University of California, San Francisco
Peng Zhang, MD, PhD
- Department of Veterans Affairs Medical Center, San Francisco, Calif
Michael A. Guttman, MS
- Laboratory of Cardiac Energetics, National Institutes of Health–National Heart Lung and Blood Institute, Bethesda, Md
Cengizhan Ozturk, MD, PhD
- Laboratory of Cardiac Energetics, National Institutes of Health–National Heart Lung and Blood Institute, Bethesda, Md
Elliot R. McVeigh, PhD
- Laboratory of Cardiac Energetics, National Institutes of Health–National Heart Lung and Blood Institute, Bethesda, Md
Arthur W. Wallace, MD, PhD
- Department of Veterans Affairs Medical Center, San Francisco, Calif
- Department of Anesthesia, University of California, San Francisco
David A. Saloner, PhD
- Department of Veterans Affairs Medical Center, San Francisco, Calif
- Department of Radiology, University of California, San Francisco
Mark B. Ratcliffe, MD
- Department of Surgery, University of California, San Francisco
- Department of Veterans Affairs Medical Center, San Francisco, Calif

Received 20 January 2005 ,Revised 11 July 2005 ,Accepted 19 July 2005.

Long-axis MR images after myocardial infarction (A) and 10 days after plication (B) in sheep. MI, Dykinetic infarct; SI, septal infarct; IP, infarct plication.

Long-axis MR images after myocardial infarction (A) and 10 days after plication (B) in sheep. MI, Dykinetic infarct; SI, septal infarct; IP, infarct plication.
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Effects of aneurysm plication on selected end-systolic strain tensor components. A, Circumferential strain versus distance from LV base. B, Longitudinal strain versus distance from LV base. C, Circumf

Effects of aneurysm plication on selected end-systolic strain tensor components. A, Circumferential strain versus distance from LV base. B, Longitudinal strain versus distance from LV base. C, Circumferential strain versus quadrant. D, Longitudinal strain versus quadrant.
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End-diastolic 3-dimensional tagged MRI data set. A, Five short-axis (separated by 1 cm) and one long-axis image planes/slices. B, Six long-axis (equally separated by 30° around the LV circumference) a

End-diastolic 3-dimensional tagged MRI data set. A, Five short-axis (separated by 1 cm) and one long-axis image planes/slices. B, Six long-axis (equally separated by 30° around the LV circumference) and one short-axis image slices. The endocardial contours are highlighted in green and yellow.
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A, Time series throughout systole of the 3-dimensional Green strain component in the local circumferential direction (Ecc) at the midwall (shell 2) of 12 different sectors in a short-axis plane/slice

A, Time series throughout systole of the 3-dimensional Green strain component in the local circumferential direction (Ecc) at the midwall (shell 2) of 12 different sectors in a short-axis plane/slice that was near the border zone at end-diastole (time 1) of a sheep before its anteroapical LV aneurysm was plicated. B, Sectors 2, 5, 8, and 11 correspond to the central/middle portions of the posterior LV wall, lateral LV wall, anterior LV wall, and interventricular septum, respectively.
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End-diastolic (A) and end-systolic (B) long-axis tagged MR images of sheep heart with LV aneurysm. Note the significant through-plane motion, which varies monotonically from approximately the tag spac

End-diastolic (A) and end-systolic (B) long-axis tagged MR images of sheep heart with LV aneurysm. Note the significant through-plane motion, which varies monotonically from approximately the tag spacing (8 mm) near the LV base to zero near the apex.
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Effect of aneurysm plication on LV volume.

Effect of aneurysm plication on LV volume.
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Longitudinal variation in selected end-systolic strain tensor components before aneurysm plication. A, Circumferential strain. B, Longitudinal strain. C, Shear strain in the radial-circumferential pla

Longitudinal variation in selected end-systolic strain tensor components before aneurysm plication. A, Circumferential strain. B, Longitudinal strain. C, Shear strain in the radial-circumferential plane. D, Shear strain in the radial-longitudinal plane. E, Shear strain in the circumferential-longitudinal plane. These plots represent aggregate absolute baseline strains versus distance from base. Error bars indicate 1 standard deviation.
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This study was supported by National Institutes of Health grant R01-HL58759 (Dr Guccione), Veterans Administration Merit Review (Dr Wallace), R01-HL-63348 (Dr Ratcliffe), and a predoctoral fellowship from the American Heart Association (Mr. Walker).

PII: S0022-5223(05)01759-9

doi: 10.1016/j.jtcvs.2005.07.065

« Previous Next » The Journal of Thoracic and Cardiovascular Surgery
Volume 131, Issue 3 , Pages 579-586.e3 , March 2006