The Journal of Thoracic and Cardiovascular Surgery
Volume 130, Issue 6 , Pages 1523-1530 , December 2005

Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion

  • Catherine L. Dent, MD

      Affiliations

    • Departments of Pediatrics (Divisions of Cardiology
    • Corresponding Author InformationAddress for reprints: Catherine Dent, MD, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 2003, Cincinnati, OH 45229-3039
  • ,
  • James P. Spaeth, MD

      Affiliations

    • Anesthesiology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio
  • ,
  • Blaise V. Jones, MD

      Affiliations

    • Radiology
  • ,
  • Steven M. Schwartz, MD

      Affiliations

    • Departments of Pediatrics (Divisions of Cardiology
  • ,
  • Tracy A. Glauser, MD

      Affiliations

    • Neurology
  • ,
  • Barbara Hallinan, MD, PhD

      Affiliations

    • Neurology
  • ,
  • Jeffrey M. Pearl, MD

      Affiliations

    • Surgery (Division of Cardiothoracic Surgery)
  • ,
  • Philip R. Khoury, MS

      Affiliations

    • Departments of Pediatrics (Divisions of Cardiology
    • Epidemiology/Biostatistics)
  • ,
  • C. Dean Kurth, MD

      Affiliations

    • Anesthesiology, Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, Cincinnati, Ohio

References 

  1. Kern JH , Hinton VJ , Nereo NE , Hayes CJ , Gersony WM . Early developmental outcome after the Norwood procedure for hypoplastic left heart syndrome . Pediatrics . 1998;102:1148–1152
  2. Goldberg CS , Schwartz EM , Brunberg JA , et al.  Neurodevelopmental outcome of patients after the Fontan operation: a comparison between children with hypoplastic left heart syndrome and other functional single ventricle lesions . J Pediatr . 2000;137:646–652
  3. Wernovsky G , Stiles KM , Gauvreau K , et al.  Cognitive development after the Fontan operation . Circulation . 2000;102:883–889
  4. Rogers BT , Msall ME , Buck GM , et al.  Neurodevelopmental outcome of infants with hypoplastic left heart syndrome . J Pediatr . 1995;126:496–498
  5. Mahle WT , Clancy RR , Moss EM , Gerdes M , Jobes DR , Wernovsky G . Neurodevelopmental outcome and lifestyle assessment in school-aged and adolescent children with hypoplastic left heart syndrome . Pediatrics . 2000;105:1082–1089
  6. Neurologic sequelae associated with deep hypothermic circulatory arrest . Ann Thorac Surg. . 1998;65(suppl):S65–S70 , S74-6
  7. Newburger JW , Jonas RA , Wernovsky G , et al.  A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery . N Engl J Med . 1993;329:1057–1064
  8. Bellinger DC , Jonas RA , Rappaport LA , et al.  Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass . N Engl J Med . 1995;332:549–555
  9. Neurodevelopmental outcomes in children after the Fontan operation . Circulation. . 2001;104(suppl I):I127–I132
  10. Wypij D , Newburger JW , Rappaport LA , et al.  The effect of duration of deep hypothermic circulatory arrest in infant heart surgery on late neurodevelopment: the Boston Circulatory Arrest Trial . J Thorac Cardiovasc Surg . 2003;126:1397–1403
  11. Glauser TA , Rorke LB , Weinberg PM , Clancy RR . Acquired neuropathologic lesions associated with the hypoplastic left heart syndrome . Pediatrics . 1990;85:991–1000
  12. Mahle WT , Tavani F , Zimmerman RA , et al.  An MRI study of neurological injury before and after congenital heart surgery . Circulation. . 2002;106(suppl I):I109–I114
  13. Pigula FA , Nemoto EM , Griffith BP , Siewers RD . Regional low-flow perfusion provides cerebral circulatory support during neonatal aortic arch reconstruction . J Thorac Cardiovasc Surg . 2000;119:331–339
  14. Myung RJ , Petko M , Judkins AR , et al.  Regional low-flow perfusion improves neurologic outcome compared with deep hypothermic circulatory arrest in neonatal piglets . J Thorac Cardiovasc Surg . 2004;127:1051–1057
  15. Wernovsky G , Wypij D , Jonas RA , et al.  Postoperative course and hemodynamic profile after the arterial switch operation in neonates and infants (A comparison of low-flow cardiopulmonary bypass and circulatory arrest) . Circulation . 1995;92:2226–2235
  16. Shore S , Nelson DP , Pearl JM , et al.  Usefulness of corticosteroid therapy in decreasing epinephrine requirements in critically ill infants with congenital heart disease . Am J Cardiol . 2001;88:591–594
  17. Morris CD , Outcalt J , Menashe VD . Hypoplastic left heart syndrome: natural history in a geographically defined population . Pediatrics . 1990;85:977–983
  18. Licht DJ , Wang J , Silvestre DW , et al.  Preoperative cerebral blood flow is diminished in neonates with severe congenital heart defects . J Thorac Cardiovasc Surg . 2004;128:841–849
  19. Donofrio MT , Bremer YA , Schieken RM , et al.  Autoregulation of cerebral blood flow in fetuses with congenital heart disease: the brain sparing effect . Pediatr Cardiol . 2003;24:436–443
  20. Kaltman JR , Di H , Tian Z , Rychik J . Impact of congenital heart disease on cerebrovascular blood flow dynamics in the fetus . Ultrasound Obstet Gynecol . 2005;25:32–36
  21. Kurth CD , Steven JL , Montenegro LM , et al.  Cerebral oxygen saturation before congenital heart surgery . Ann Thorac Surg . 2001;72:187–192
  22. Jonas RA , Bellinger DC , Rappaport LA , et al.  Relation of pH strategy and developmental outcome after hypothermic circulatory arrest . J Thorac Cardiovasc Surg . 1993;106:362–368
  23. Bellinger DC , Wypij D , duDuplessis AJ , et al.  Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: the Boston Circulatory Arrest Trial . J Thorac Cardiovasc Surg . 2003;126:1385–1396
  24. Hoffman GM , Ghanayem NS , Stuth EA , Berens RJ , Tweddell JS . NIRS-derived somatic and cerebral saturation difference provides non-invasive real time hemodynamic assessment of cardiogenic shock and anaerobic metabolism [abstract] . Anesthesiology . 2004;101:A1448
  25. Kurth CD , Levy WJ , McCann J . Near-infrared spectroscopy cerebral oxygen saturation thresholds for hypoxia-ischemia in piglets . J Cereb Blood Flow Metab . 2002;22:335–341
  26. Sakamoto T , Hatsuoka S , Stock UA , et al.  Prediction of safe duration of hypothermic circulatory arrest by near-infrared spectroscopy . J Thorac Cardiovasc Surg . 2001;122:339–350
  27. Austin EH , Edmonds HL , Auden SM , et al.  Benefit of neurophysiologic monitoring for pediatric cardiac surgery . J Thorac Cardiovasc Surg . 1997;114:707–717
  28. Skranes JS , Vik T , Nilsen G , et al.  Cerebral magnetic resonance imaging (MRI) and mental and motor function of very low birth weight infants at one year of corrected age . Neuropediatrics . 1993;24:256–262
  29. Olsen P , Vainionpaa L , Paakko E , Korkman M , Pyhtinen J , Jarvelin MR . Psychological findings in preterm children related to neurologic status and magnetic resonance imaging . Pediatrics . 1998;102:329–336

PII: S0022-5223(05)01369-3

doi: 10.1016/j.jtcvs.2005.07.051

The Journal of Thoracic and Cardiovascular Surgery
Volume 130, Issue 6 , Pages 1523-1530 , December 2005