The Journal of Thoracic and Cardiovascular Surgery
Volume 130, Issue 6 , Pages 1511-1516 , December 2005

Effect of congenital heart disease on neurodevelopmental outcomes within multiple-gestation births

  • Amy H. Schultz, MD

      Affiliations

    • Divisions of Cardiology, General Pediatrics
    • Corresponding Author InformationAddress for reprints: Amy H. Schultz, MD, Division of Cardiology, Children's Hospital and Regional Medical Center, 4800 Sand Point Way, W-4841, Seattle, WA 98105
    • ,
  • Gail P. Jarvik, MD, PhD

      Affiliations

    • Department of Medicine, University of Washington, Seattle, Wash
    • ,
  • Gil Wernovsky, MD

      Affiliations

    • Divisions of Cardiology, General Pediatrics
    • ,
  • Judy Bernbaum, MD

      Affiliations

    • Neurology
    • ,
  • Robert R. Clancy, MD

      Affiliations

    • Psychology
    • ,
  • Jo Ann D'Agostino, CRNP

      Affiliations

    • Neurology
    • ,
  • Marsha Gerdes, PhD

      Affiliations

    • Genetics
    • ,
  • Donna McDonald-McGinn, MS, CGC

      Affiliations

    • Cardiothoracic Surgery
    • ,
  • Susan C. Nicolson, MD

      Affiliations

    • The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, Pa, and the Division of Medical Genetics
    • ,
  • Thomas L. Spray, MD

      Affiliations

    • Department of Anesthesia and Critical Care Medicine
    • ,
  • Elaine Zackai, MD

      Affiliations

    • Cardiothoracic Surgery
    • ,
  • J. William Gaynor, MD

      Affiliations

    • Department of Anesthesia and Critical Care Medicine

Received 16 May 2005 ,Revised 29 June 2005 ,Accepted 12 July 2005.

References 

  1. Bellinger DC , Wypij D , du Plessis AJ , Rappaport LA , Jonas RA , Wernovsky G , et al.  Neurodevelopmental status at eight years in children with dextro-transposition of the great arteries: the Boston Circulatory Arrest Trial . J Thorac Cardiovasc Surg . 2003;126:1385–1396
  2. Wernovsky G , Stiles KM , Gauvreau K , Gentles TL , duPlessis AJ , Bellinger DC , et al.  Cognitive development after the Fontan operation . Circulation . 2000;102:883–889
  3. Mahle WT , Clancy RR , Moss EM , Gerdes M , Jobes DR , Wernovsky G . Neurodevelopmental outcome and lifestyle assessment in school-aged and adolescent children with hypoplastic left heart syndrome . Pediatrics . 2000;105:1082–1089
  4. Gaynor JW , Gerdes M , Zackai EH , Bernbaum J , Wernovsky G , Clancy RR , et al.  Apolipoprotein E genotype and neurodevelopmental sequelae of infant cardiac surgery . J Thorac Cardiovasc Surg . 2003;126:1736–1745
  5. Devlin B , Daniels M , Roeder K . The heritability of IQ . Nature . 1997;388:468–471
  6. Bouchard TJ , McGue M . Genetic and environmental influences on human psychological differences . J Neurobiol . 2003;54:4–45
  7. Petrill SA , Deater-Deckard K . Task orientation, parental warmth and SES account for a significant proportion of the shared environmental variance in general cognitive ability in early childhood: evidence from a twin study . Dev Sci . 2004;7:25–32
  8. Bhutta AT , Cleves MA , Casey PH , Cradock MM , Anand KJ . Cognitive and behavioral outcomes of school-aged children who were born preterm: a meta-analysis . JAMA . 2002;288:728–737
  9. Forbess JM , Visconti KJ , Hancock-Friesen C , Howe RC , Bellinger DC , Jonas RA . Neurodevelopmental outcome after congenital heart surgery: results from an institutional registry . Circulation . 2002;106:95–102
  10. Hollingshead A . Four factor index of social status . New Haven: Conn: Department of Sociology, Yale University; 1975;
  11. Clancy RR , McGaurn SA , Wernovsky G , Spray TL , Norwood WI , Jacobs ML , et al.  Preoperative risk-of-death prediction model in heart surgery with deep hypothermic circulatory arrest in the neonate . J Thorac Cardiovasc Surg . 2000;119:347–357
  12. Bellinger DC , Jonas RA , Rappaport LA , Wypij D , Wernovsky G , Kuban KC , et al.  Developmental and neurologic status of children after heart surgery with hypothermic circulatory arrest or low-flow cardiopulmonary bypass . N Engl J Med . 1995;332:549–555
  13. Jonas RA , Wypij D , Roth SJ , Bellinger DC , Visconti KJ , du Plessis AJ , et al.  The influence of hemodilution on outcome after hypothermic cardiopulmonary bypass: results of a randomized trial in infants . J Thorac Cardiovasc Surg . 2003;126:1765–1774
  14. Galli KK , Zimmerman RA , Jarvik GP , Wernovsky G , Kuypers MK , Clancy RR , et al.  Periventricular leukomalacia is common after neonatal cardiac surgery . J Thorac Cardiovasc Surg . 2004;127:692–704
  15. McGrath E , Wypij D , Rappaport LA , Newburger JW , Bellinger DC . Prediction of IQ and achievement at age 8 years from neurodevelopmental status at age 1 year in children with D-transposition of the great arteries . Pediatrics . 2004;114:e572–e576
  16. Feldman R , Eidelman AI . Does a triplet birth pose a special risk for infant development? . Assessing cognitive development in relation to intrauterine growth and mother-infant interaction across the first 2 years. Pediatrics . 2005;115:443–452

 Supported by an American Heart Association National Grant-in-Aid (9950480N), the Pew Biomedical Scholar Program, the Fannie E. Rippel Foundation and NIH T32-HL07915 (Dr Schultz).

PII: S0022-5223(05)01278-X

doi: 10.1016/j.jtcvs.2005.07.040

The Journal of Thoracic and Cardiovascular Surgery
Volume 130, Issue 6 , Pages 1511-1516 , December 2005

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