The Journal of Thoracic and Cardiovascular Surgery
Volume 130, Issue 6 , Pages 1511-1516 , December 2005

Effect of congenital heart disease on neurodevelopmental outcomes within multiple-gestation births

  • Amy H. Schultz, MD

      Affiliations

    • Divisions of Cardiology, General Pediatrics
    • Corresponding Author InformationAddress for reprints: Amy H. Schultz, MD, Division of Cardiology, Children's Hospital and Regional Medical Center, 4800 Sand Point Way, W-4841, Seattle, WA 98105
    • ,
  • Gail P. Jarvik, MD, PhD

      Affiliations

    • Department of Medicine, University of Washington, Seattle, Wash
    • ,
  • Gil Wernovsky, MD

      Affiliations

    • Divisions of Cardiology, General Pediatrics
    • ,
  • Judy Bernbaum, MD

      Affiliations

    • Neurology
    • ,
  • Robert R. Clancy, MD

      Affiliations

    • Psychology
    • ,
  • Jo Ann D'Agostino, CRNP

      Affiliations

    • Neurology
    • ,
  • Marsha Gerdes, PhD

      Affiliations

    • Genetics
    • ,
  • Donna McDonald-McGinn, MS, CGC

      Affiliations

    • Cardiothoracic Surgery
    • ,
  • Susan C. Nicolson, MD

      Affiliations

    • The Children's Hospital of Philadelphia and the University of Pennsylvania School of Medicine, Philadelphia, Pa, and the Division of Medical Genetics
    • ,
  • Thomas L. Spray, MD

      Affiliations

    • Department of Anesthesia and Critical Care Medicine
    • ,
  • Elaine Zackai, MD

      Affiliations

    • Cardiothoracic Surgery
    • ,
  • J. William Gaynor, MD

      Affiliations

    • Department of Anesthesia and Critical Care Medicine

Received 16 May 2005 ,Revised 29 June 2005 ,Accepted 12 July 2005.

  • Image Result

    Comparison of Mental Development Index (MDI) scores at 1 year of age within multiple-gestation births. Families are ordered by increasing gestational age at birth. Cardiac diagnosis in the child with

    Comparison of Mental Development Index (MDI) scores at 1 year of age within multiple-gestation births. Families are ordered by increasing gestational age at birth. Cardiac diagnosis in the child with congenital heart disease is indicated below gestational age. Families 2 and 3 are sets of triplets; consequently, results for 2 sibling control subjects are shown. The horizontal line at MDI of 100 represents the population norm. TAPVR, Total anomalous pulmonary venous return; D-TGA, d-transposition of the great arteries; TOF, tetralogy of Fallot; PA, pulmonary atresia; IVS, intact ventricular septum; HLHS, hypoplastic left heart syndrome; AS, aortic stenosis.

  • Image Result
    Comparison of Psychomotor Development Index (PDI) scores at 1 year of age within multiple-gestation births. Families are ordered by increasing gestational age at birth. Cardiac diagnosis in the child

    Comparison of Psychomotor Development Index (PDI) scores at 1 year of age within multiple-gestation births. Families are ordered by increasing gestational age at birth. Cardiac diagnosis in the child with congenital heart disease is indicated below gestational age. Families 2 and 3 are sets of triplets; consequently, results for 2 sibling control subjects are shown. The horizontal line at PDI of 100 represents the population norm. TAPVR, Total anomalous pulmonary venous return; D-TGA, d-transposition of the great arteries; TOF, tetralogy of Fallot; PA, pulmonary atresia; IVS, intact ventricular septum; HLHS, hypoplastic left heart syndrome; AS, aortic stenosis.

 Supported by an American Heart Association National Grant-in-Aid (9950480N), the Pew Biomedical Scholar Program, the Fannie E. Rippel Foundation and NIH T32-HL07915 (Dr Schultz).

PII: S0022-5223(05)01278-X

doi: 10.1016/j.jtcvs.2005.07.040

The Journal of Thoracic and Cardiovascular Surgery
Volume 130, Issue 6 , Pages 1511-1516 , December 2005

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