The Journal of Thoracic and Cardiovascular Surgery
Volume 130, Issue 5 , Pages 1278-1286 , November 2005

Increasing duration of deep hypothermic circulatory arrest is associated with an increased incidence of postoperative electroencephalographic seizures

Read at the Eighty-fourth Annual Meeting of The American Association for Thoracic Surgery, Toronto, Ontario, Canada, April 25-28, 2004.

  • J. William Gaynor, MD

      Affiliations

    • Division of Cardiothoracic Surgery, The Cardiac Center at The Children’s Hospital of Philadelphia, Philadelphia, Pa
    • Corresponding Author InformationAddress for reprints: J. William Gaynor, MD, Division of Cardiothoracic Surgery, The Children’s Hospital of Philadelphia, 34th and Civic Center Blvd, Suite 8527, Philadelphia, PA 19104
    • ,
  • Susan C. Nicolson, MD

      Affiliations

    • Division of Cardiothoracic Anesthesiology, The Cardiac Center at The Children’s Hospital of Philadelphia, Philadelphia, Pa
    • ,
  • Gail P. Jarvik, MD, PhD

      Affiliations

    • Department of Medicine (Medical Genetics), University of Washington, Seattle Wash
    • ,
  • Gil Wernovsky, MD

      Affiliations

    • Division of Pediatric Cardiology, The Cardiac Center at The Children’s Hospital of Philadelphia, Philadelphia, Pa
    • ,
  • Lisa M. Montenegro, MD

      Affiliations

    • Division of Cardiothoracic Anesthesiology, The Cardiac Center at The Children’s Hospital of Philadelphia, Philadelphia, Pa
    • ,
  • Nancy B. Burnham, RN, MSN

      Affiliations

    • Division of Cardiothoracic Surgery, The Cardiac Center at The Children’s Hospital of Philadelphia, Philadelphia, Pa
    • ,
  • Diane M. Hartman, RN

      Affiliations

    • Division of Cardiothoracic Surgery, The Cardiac Center at The Children’s Hospital of Philadelphia, Philadelphia, Pa
    • ,
  • Andy Louie

      Affiliations

    • Department of Medicine (Medical Genetics), University of Washington, Seattle Wash
    • ,
  • Thomas L. Spray, MD

      Affiliations

    • Division of Cardiothoracic Surgery, The Cardiac Center at The Children’s Hospital of Philadelphia, Philadelphia, Pa
    • ,
  • Robert R. Clancy, MD

      Affiliations

    • Division of Neurology, The Cardiac Center at The Children’s Hospital of Philadelphia, Philadelphia, Pa

Received 24 April 2004 ,Revised 16 November 2004 ,Accepted 7 February 2005.

  • Image Result

    Relationship of EEG seizures to cardiac defect. The number of patients in each group with and without seizures is shown on the y-axis.

    Relationship of EEG seizures to cardiac defect. The number of patients in each group with and without seizures is shown on the y-axis.

  • Image Result

    Relationship between duration of DHCA and occurrence of an EEG seizure. Patients are grouped according to total DHCA time in 5-minute intervals. The number of patients in each group with and without a

    Relationship between duration of DHCA and occurrence of an EEG seizure. Patients are grouped according to total DHCA time in 5-minute intervals. The number of patients in each group with and without an EEG seizure is shown on the y-axis.

  • Image Result
    Comparison of incidence of seizures among continuous CPB alone, DHCA for 40 minutes or less, and DHCA for greater than 40 minutes.

    Comparison of incidence of seizures among continuous CPB alone, DHCA for 40 minutes or less, and DHCA for greater than 40 minutes.

 Supported by a grant from the Fannie E. Rippel Foundation, an American Heart Association National Grant-in-Aid (9950480N), and a grant HL071834 from the National Institutes of Health.

PII: S0022-5223(05)00532-5

doi: 10.1016/j.jtcvs.2005.02.065

The Journal of Thoracic and Cardiovascular Surgery
Volume 130, Issue 5 , Pages 1278-1286 , November 2005

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