The Journal of Thoracic and Cardiovascular Surgery
Volume 123, Issue 3 , Pages 409-410 , March 2002

Molecular biologic substaging of non-small cell lung cancer

Received 25 July 2001 ,Accepted 13 September 2001.

References 

  1. Greenlee RT, Hill-Harmon MB, Murray T, Thun M. Cancer statistics, 2001. CA Cancer J Clin. 2001;51:15–36
  2. Mountain CF. Revisions in the international staging system for lung cancer. Chest. 1997;111:1710–1717
  3. Naruke T, Tsuchiya R, Kondo H, Asamura H. Prognosis and survival after resection for bronchogenic carcinoma based on the 1997 TNM-staging classification: the Japanese experience. Ann Thorac Surg. 2001;71:1759–1764
  4. D'Amico TA, Massey M, Herndon JE, Moore MB, Harpole DH. A biologic risk model for stage I lung cancer: immunohistochemical analysis of 408 patients with the use of ten molecular markers. J Thorac Cardiovasc Surg. 1999;117:736–743
  5. Wu J, Ohta Y, Minato H, Tsunezuka Y, Oda M, Watanabe Y, et al.  Nodal occult metastasis in patients with peripheral lung adenocarcinoma of 2.0 cm or less in diameter. Ann Thorac Surg. 2001;71:1772–1777
  6. Maruyama R, Sugio K, Mitsudomi T, Saitoh G, Ishida T, Sugimachi K. Relationship between early recurrence and micrometastases in the lymph nodes of patients with stage I non-small-cell lung cancer. J Thorac Cardiovasc Surg. 1997;114:535–543
  7. Hashimoto T, Kobayashi Y, Ishikawa Y, Tsuchiya S, Okumura S, Nakagawa K, et al.  Prognostic value of genetically diagnosed lymph node micrometastasis in non-small cell lung carcinoma cases. Cancer Res. 2000;60:6472–6478
  8. Ohta Y, Nozawa H, Tanaka Y, Oda M, Watanabe Y. Increased vascular endothelial growth factor and vascular endothelial growth factor-c and decreased nm23 expression associated with microdissemination in the lymph nodes in stage I non-small cell lung cancer. J Thorac Cardiovasc Surg. 2000;119:804–813
  9. Baselga J. New therapeutic agents targeting the epidermal growth factor receptor. J Clin Oncol. 2000;18(21 Suppl):54S–59S
  10. Ahrendt SA, Yang SC, Wu L, Roig CM, Russell P, Westra WH, et al.  Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study. J Thorac Cardiovasc Surg. 2002;123:466–474
  11. D'Amico TA, Aloia TA, Moore MB, Herndon JE, Brooks KR, Lau CL, et al.  Molecular biologic substaging of stage I lung cancer according to gender and histology. Ann Thorac Surg. 2000;69:882–886
  12. Liptay MJ, Masters GA, Winchester DJ, Edelman BL, Garrido BJ, Hirschtritt TR, et al.  Intraoperative radioisotope sentinel lymph node mapping in non-small cell lung cancer. Ann Thorac Surg. 2000;70:384–389

 Address for reprints: Thomas A. D'Amico, MD, Department of Surgery, Duke University Medical Center, Box 3496, Durham, NC 27710.

PII: S0022-5223(02)88066-7

doi: 10.1067/mtc.2002.120339

The Journal of Thoracic and Cardiovascular Surgery
Volume 123, Issue 3 , Pages 409-410 , March 2002