The Journal of Thoracic and Cardiovascular Surgery
Volume 125, Issue 1 , Pages 184-190 , January 2003

Does aprotinin influence the inflammatory response to cardiopulmonary bypass in patients?

Presented in part at the Annual Meeting of the American Society of Anesthesiologists, Orlando, Fla, October 1998.

Received 16 April 2001 ,Revised 25 July 2001 ,Accepted 15 November 2001.

  • Image Result

    Time course of TNF-α, IL-6, IL-8, and IL-10 in the 3 groups of patients. CTRL, Control; LD, low dose; HD, high dose.

    Time course of TNF-α, IL-6, IL-8, and IL-10 in the 3 groups of patients. CTRL, Control; LD, low dose; HD, high dose.

  • Image Result

    Time course of prekallikrein, PGD2, and C4a in the 3 groups of patients. CTRL, Control; LD, low dose; HD, high dose.

    Time course of prekallikrein, PGD2, and C4a in the 3 groups of patients. CTRL, Control; LD, low dose; HD, high dose.

  • Image Result

    Blood loss in the 3 groups of patients. CTRL, Control; LD, low dose; HD, high dose.

    Blood loss in the 3 groups of patients. CTRL, Control; LD, low dose; HD, high dose.

 This work was supported by a grant from Bayer, Leverkusen, Germany.

☆☆ Address for reprints: Denis Schmartz, MD, Department of Anesthesiology, Erasme University Hospital, 808 route de Lennik, B-1070 Brussels, Belgium (E-mail: denis.schmartz@ulb.ac.be).

PII: S0022-5223(02)73311-4

doi: 10.1067/mtc.2003.64

The Journal of Thoracic and Cardiovascular Surgery
Volume 125, Issue 1 , Pages 184-190 , January 2003