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The Journal of Thoracic and Cardiovascular Surgery
Volume 124, Issue 3
, Pages 435-441
, September 2002
The endothelin antagonist BQ123 reduces pulmonary vascular resistance after surgical intervention for congenital heart disease
References
- Pulmonary hypertension after operations for congenital heart disease: analysis of risk factors and management. J Thorac Cardiovasc Surg. 1996;112:1600–1609
-
L-Arginine and substance P reverse the pulmonary endothelial dysfunction caused by congenital heart surgery.
Circulation. 1999;100:749–755
- Cardiopulmonary bypass and circulatory arrest increase endothelin-1 production and receptor expression in the lung. J Thorac Cardiovasc Surg. 1997;113:777–783
- Increased plasma levels of endothelin-1 after cardiopulmonary bypass in patients with pulmonary hypertension and congenital heart disease. J Thorac Cardiovasc Surg. 1993;106:473–478
-
Dynamic changes of endothelin-1, nitric oxide, and cyclic GMP in patients with congenital heart disease.
Circulation. 1997;96:II-346–II-351
- Endothelin receptor blockade prevents the rise in pulmonary vascular resistance after cardiopulmonary bypass in lambs with increased pulmonary blood flow. J Thorac Cardiovasc Surg. 1999;117:314–323
- . Blocking of the endothelin system: the development of receptor antagonists. Pulm Pharmacol Ther. 1998;11:97–112
- Effect of BQ13 on vasoconstriction as a result of either hypoxia or endothlin-1 in perfused rat lungs. Acta Physiol Scand. 1995;155:53–60
- . Short-term haemodynamic effects of BQ-123, a selective endothelin (ET9A)-receptor antagonist in chronic heart failure. Lancet. 1998;352:201–202
- . A successful modification of ultrafiltration for cardiopulmonary bypass in children. Perfusion. 1991;6:41–50
-
.
Respiratory mass spectrometry: ‘on line’ computer control and data processing.
J Physiol (Lond. 1973;231:80P–81P
-
Negative-pressure ventilation improves cardiac output after right heart surgery.
Circulation. 1996;94:II-49–II-55
- Plasma endothelin-1 like immunoreactivity levels in neonates. Eur J Pediatr. 1992;151:913–915
- Primary pulmonary hypertension between inflammation and cancer. Chest. 1998;114:225S–230S
- . Clinical insights into the pathogenesis of primary pulmonary hypertension. Chest. 1998;114:237S–241S
- . Endothelial dysfunction in pulmonary vascular disorders. Arzneimittelforschung. 1994;44:451–454
- . Impairment of endothelium-dependent pulmonary artery relaxation in children with congenital heart disease and abnormal pulmonary hemodynamics. Circulation. 1993;87:440–446
- Use of inhaled nitric oxide and acetylcholine in the evaluation of pulmonary hypertension and endothelial function after cardiopulmonary bypass. Circulation. 1993;88:2128–2138
- Inhaled nitric oxide in persistent pulmonary hypertension of the newborn. Lancet. 1992;340:818–819
- Inhaled nitric oxide for the adult respiratory distress syndrome. N Engl J Med. 1993;238:399–405
- Inhaled nitric oxide treatment for stabilization and emergency medical transport of critically ill newborns and infants. Pediatrics. 1995;95:773–776
- Complement and contact activation during cardiovascular operations in infants. Ann Thorac Surg. 1998;65:525–531
- Cardiopulmonary bypass and pulmonary thromboxane generation. Ann Thorac Surg. 1993;55:724–728
- Human pulmonary circulation is an important site for both clearance and production of endothelin-1. Circulation. 1996;94:1578–1584
- Circulating endothelin is not extracted by the pulmonary circulation in man. Chest. 1992;102:1143–1144
- Absence of pulmonary endothelin gradient in patients with normal or elevated circulating endothelin. Am J Cardiol. 1994;73:1015–1016
- Down-regulation of ET(B) receptor, but not ET(A) receptor, in congestive lung secondary to heart failure. Are marked increases in circulating endothelin-1 partly attributable to decreases in lung ET(B) receptor-mediated clearance of endothelin-1?. Life Sci. 1998;62:185–193
- . Reduced pulmonary clearance of endothelin-1 contributes to the increase of circulating levels in heart failure secondary to myocardial infarction. Circulation. 1998;98:1684–1687
- Endothelin-1 in acute lung injury and the adult respiratory distress syndrome. Am Rev Respir Dis. 1993;148:1646–1650
- Endothelin-1 levels in infants with pulmonary hypertension receiving extracorporeal membrane oxygenation. J Perinat Med. 1999;27:216–220
- Circulating immunoreactive endothelin-1 in children with pulmonary hypertension. Association with acute hypoxic pulmonary vasoreactivity. Am Rev Respir Dis. 1993;148:519–522
- Endothelin-1 in the lungs of patients with pulmonary hypertension. Cardiovasc Res. 1997;33:196–200
- Expression of endothelin-1 in the lungs of patients with pulmonary hypertension. N Engl J Med. 1993;328:1732–1739
- Relation between L-arginine-nitric oxide pathway and endothelin-1 effects in periaqueductal gray area of rats. J Cardiovasc Pharmacol. 1994;24:974–978
- Modulation of ET-1-induced contraction of human bronchi by airway epithelium-dependent nitric oxide release via ET(A) receptor activation. Br J Pharmacol. 1999;126:529–535
☆ This work was made possible by a grant from the National Heart Research Fund (No. 99-CC-10), Leeds, United Kingdom.
☆☆ Address for reprints: D. J. Penny, MD, Cardiology Department, Royal Children's Hospital, Flemington Rd, Parkville, Victoria 3052, Australia (E-mail: pennyd@cryptic.rch.unimelb.edu.au).
PII: S0022-5223(02)00104-6
doi: 10.1067/mtc.2002.121492
© 2002 American Association for Thoracic Surgery. Published by Elsevier Inc. All rights reserved.
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The Journal of Thoracic and Cardiovascular Surgery
Volume 124, Issue 3
, Pages 435-441
, September 2002
